In Vitro Skin Irritation Test

ABSTRACT

Considering animal welfare concerns alternative in vitro test methods for skin corrosion/irritation testing have been validated and accepted as full replacement tests by applying a tiered testing strategy (see Annex to OECD 404, 2002). We examined one amine derivative to determine best suitable test methods for classification of several substances of the same chemical class using the following methods in consecutive steps:

Please click on the following link for the full article.
In Vitro Skin Irritation Test