MEGGLE Excipients & Technology Contract Manufacturing

Overview

MEGGLE’s Excipients & Technology business division is not just one of the world’s most respected manufacturers of lactose-based pharmaceutical ingredients and excipients worldwide but can also provide contract manufacturing services for its clients from the food, life sciences and pharmaceutical industries.

MEGGLE can take on projects involving spray drying, high shear agglomeration or evaporation. All facilities are state of the art to realize customers’ specific requirements, even highly unusual ones, to very high standards of quality, reliability and accuracy.

The MEGGLE contract manufacturing offer has been upgraded with new and more advanced facilities and is now supported by its own dedicated website.

CMO service portfolio

As a Contract Manufacturing Organization (CMO), MEGGLE Excipients & Technology can offer a wide range of different technical processes and facilities from its modern plants at Wasserburg. These include:

• Agglomeration
• Spray Drying
• High shear agglomeration

Evaporation

MEGGLE is also able to offer more specialized processes. These include:

• Chemical and/or physical analytics incl. microbiology
• All options for SEM/DVS/ laser diffractometry/ HPLC/FT4 (rheometry)
• Comprehensive logistics services – including GDP storage and organization of transportation
• Process design consultancy

Facilities

The modern MEGGLE facilities at Wasserburg include eight advanced spray dryers, five fluidized bed dryers and 10 Evaporators.

• Spray Drying Towers: Agglomeration can be achieved by various nozzle atomization of solutions, dispersions and emulsions at up to 200 bars pressure for enhanced product properties like improved powder characteristics, dispersibility and increased PSD. Spray drying capacity varied from 1500 to 3000 kilograms per hour – water evaporation. In addition one processing plant is equipped with a homogenizer unit applying up to 600 bars for various emulsions.
• Agglomerator: Using High-Shear-Granulator with subsequent fluidized bed drying, MEGGLE can greatly enhance product properties with improved powder characteristics, increased PSD, etc. MEGGLE’s agglomerators boast additional capabilities such as continuous mixing of up to three substances simultaneously.
• Evaporators: Falling-film evaporators with mechanical/thermal vapor recompression can withdraw water from product at up to 10.000 liters per hour, to achieve maximum concentration of product.

All manufactured products can be packaged in paper sacks (15 – 25 kg) or in Big Bag for quantities of between 500 and 1000 kg.

Quality & standards

MEGGLE recognizes that customers must meet the highest possible standards concerning the quality of products in which the smallest errors in process design or implementation can have devastating consequences.

To this end, all of MEGGLE’s facilities meet the strictest quality and regulatory requirements, including certifications according to ISO 9001:2015, ISO 14001:2004, FAMI-QS, HACCP, IPEC GMP, and EXCiPACT.

MEGGLE can also provide full process or cleaning validation for pharmaceutical products in toll manufacturing.

Resources

Click on MEGGLE Lohnfertigung for dedicated website.